When a brilliant but obsessive scientist goes to extremes to develop a universal cure for all disease, he finds himself infected with a bizarre parasite that begins to transform him into a bloodthirsty madman. Time running out, he must find a way to stop the monster that is growing within and prevent the rest of the world from being “cured.”
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Griffin, a rollerblader in the not so distant future of an economically wrecked Los Angeles, races against time to save both his younger brother and the city from the fate dealt out by the fascist rollerblading street gang, the Rollerboys.
After several years in an insane asylum, Evelyn, the keeper of the Mountaintop Motel, is released and resumes doing business. She kills her young charge out of anger, but convinces the police it was an accident – and pushed into insanity, she then proceeds to target her guests, first by releasing vermin into their rooms, but then by using her trusty sickle.